Книга: Ro60-0175: Ro4- 1539, Sedation, Euphoria (Emotion), Constipation, Itching, Respiratory Depression, Pharmacology

High Quality Content by WIKIPEDIA articles! Ro60-0175 is a drug developed by Hoffmann?La Roche, which has applications in scientific research. It acts as a potent and selective agonist for both the 5-HT2B and 5-HT2C serotonin receptor subtypes, with good selectivity over the closely related 5-HT2A subtype, and little or no affinity at other receptors. Serotonin or 5-Hydroxytryptamine (5-HT) is a monoamine neurotransmitter that is primarily found in the gastrointestinal (GI) tract and central nervous system (CNS) of humans and animals. Approximately 80 percent of the human body's total serotonin is located in the enterochromaffin cells in the gut, where it is used to regulate intestinal movements.